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Anti-insulin antibody test
The anti-insulin antibody test checks to see if your body has produced antibodies against insulin.
Antibodies are proteins the body produces to protect itself when it detects anything foreign, such as a virus or transplanted organ.
Normal Results
Normally, there are no antibodies against insulin in your blood. Antibodies can be found in the blood of many people who are taking insulin to control diabetes.
Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or test different samples. Talk to your health care provider about the meaning of your specific test results.
What Abnormal Results Mean
The presence of IgG and IgM antibodies against insulin can be part of the testing that diagnoses you with type 1 diabetes.
If you develop anti-insulin antibodies, insulin may not work as well, or it may not work at all. As a result, your blood sugar can be very high. Or the antibodies can also put you at risk for low blood sugar.
Your provider may suggest a different form of insulin to which your body may be less likely to form antibodies.
If the test shows a high level of IgE antibody against insulin, your body has developed an allergic response to the insulin.
- This could put you at risk for skin reactions where you inject insulin. You can also develop more severe reactions that affect your blood pressure or breathing.
- Medicines, such as antihistamines or low-dose injectable steroids, may help. Or you may need a treatment process called desensitization or a treatment to remove the antibodies from your blood.
Alternative Names- Insulin antibodies - serum; Insulin Ab test, Insulin resistance - insulin antibodies, Diabetes - insulin antibodies
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